This book is presented to you in an interesting way so that learning and understanding thalassemia/ haemoglobinopathy becomes less painful. Yes, we do it through case studies. Case studies are presented to simply the study of thalassemia & haemoglobinopathy which is a very wide subject and may be overwhelming to some. This book also illustrates how the knowledge of thalassemia and haemoglobinopathy is useful in the proper evaluation of test results and making diagnosis. And this may be utilised in the clinical setting in the day-to-day patient management. The cases are described clearly and would be very useful for students, doctors and physicians managing thalassemia/ haemoglobinopathy patients. This is the first series. Other volumes are under way. It can also provide a quick revision for Medical, Laboratory Technician students, MPath (Haematology) students and others especially at the last hour before the examination.